Web site designed and maintained by Chris Cairns  © SICS EBM Group 2004                                  

SICS EBMG Update No.7 September 2007

Welcome to the Scottish Intensive Care Societies Evidence-Based Medicine Groups seventh update. The new publications are listed below (Just click on the title to go to the full version).

Can I also remind you of the yahoo discussion group. The aim of this is to facilitate discussion of issues raised on the site, or to enable feedback on any publications. To subscribe to the group please email to: icu_ebm-subscribe@yahoogroups.co.uk or visit http://uk.groups.yahoo.com/group/icu_ebm/

New Critically Appraised Papers (Joint publications with JICS):

• Angstwurm, M.W.A, et al. Selenium in Intensive Care (SIC): Results of a prospective randomized, placebo-controlled, multiple-centre study in patients with severe systemic inflammatory response syndrome, sepsis and septic shock. Crit Care Med (2007) 35: 118 – 126 by Stephan Dalchow

• A Randomised Trial of Diagnostic Techniques for Ventilator-Associated Pneumonia. The Canadian Critical Care Trials Group; NEJM 2006, 355: 2619 – 2630 by Srikanth Chukkambotla and Imelda Galvin.

• Chan EY, Ruest A, O’Meade M, Cook DJ. Oral decontamination for prevention of pneumonia in mechanically ventilated adults: review and meta-analysis. BMJ 2007; 334:889-893 by Rachel Kearns

• The SAFE study investigators.  Effect of baseline serum albumin concentration on outcome of resuscitation with albumin or saline in patients in intensive care units: analysis of data from the saline versus albumin fluid evaluation (SAFE) study.  BMJ 2006; 333: 1044-49 by Erin Innes and Brian Cuthbertson.

• NKJ Adhikari, KEA Burns, JO Friedrich, JT Granton, Cook DJ, MO Meade.  Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis BMJ, doi: 10.1136/bmj.39139.716794.55 by Katrina Bramley.

New Critically Appraised Papers

• Parenteral vs. enteral nutrition in the critically ill patient: a meta-analysis of trials using the intention to treat principle.  Intensive Care Medicine 2005; 31: 12-23.  F. Simpson and G.S. Doig by Marcia McDougal

• Gao F, Melody T et al. The impact of compliance with 6-hour and 24-hour sepsis bundles on hospital mortality in patients with severe sepsis: a prospective observational study. Critical Care 2005, 9:R764-R770 (DOI 10.1186/cc3909) by Rachel Kearns.

New downloads

Updated links page

Updated Stats Page

Regards,

Chris Cairns

Chair, SICS EBMG

sicsebm@btinternet.com

Chris.Cairns@fvah.scot.nhs.uk