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SICS EBMG Update No.6 December 2006

Merry Christmas and welcome to the Scottish Intensive Care Societies Evidence-Based Medicine Groups sixth update. The new publications are listed below (Just click on the title to go to the full version).

Can I also remind you of the yahoo discussion group. The aim of this is to facilitate discussion of issues raised on the site, or to enable feedback on any publications. To subscribe to the group please email to: icu_ebm-subscribe@yahoogroups.co.uk or visit http://uk.groups.yahoo.com/group/icu_ebm/

New Critically Appraised Papers (Joint publications with JICS):

• Vinsonneau C, Camus C, Combes A, et al, on behalf of the Hemodiafe Study Group. Continuous venovenous haemodiafiltration versus intermittent haemodialysis for acute renal failure in patients with multiple organ dysfunction syndrome: a multicentre randomised trial. Lancet 2006; 368: 379-85. by Chris Cairns & Rachel Kearns

• Hochman JS, Sleeper LA, Webb JG et al for the SHOCK Trial Investigators. Early Revascularisation and Long-Term Survival in Cardiogenic Shock Complicating Acute Myocardial Infarction. JAMA 2006; 295: 2511-15. by Stephen Harris.

• Nava S, Gregoretti C, Fanfulla F, Squadrone E, Grassi M, Carlucci A, Beltrame F, Navalesi P. Noninvasive ventilation to prevent respiratory failure after extubation in high-risk patients. Crit Care Med 2005; 33: 2465-2470. by Andrew Cadamy.

New Critically Appraised Papers (SICS EBMG only):

• The National Heart, Lung and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Comparison of Two Fluid-Management Strategies in Acute Lung Injury. NEJM 2006; 354:2564-2575 by Peter Hersey

• The National Heart, Lung and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Pulmonary-Artery versus Central Venous Catheter to Guide Treatment of Acute Lung Injury. NEJM 2006; 354:2213-2224 by Peter Hersey.

• Early Non-invasive Ventilation Averts Extubation Failure in Patients at Risk. A Randomised Controlled Trial. Ferrer M, et al. Am J Respiratory and Critical Care Medicine. Jan 2006. Vol 173.pp 164-170 by Pam Doherty

• Multi-centre, cluster-randomized clinical trial of algorithms for critical-care enteral and parenteral therapy (ACCEPT). Claudio M. Martin et al for the Southwestern Ontario Critical Care Research Network. Canadian Medical Association Journal   2004: 170; 197-204 by Marcia McDougall.

• De Gans J, et al. Dexamethasone in Adults with Bacterial Meningitis. NEngl J Med 2002; 347: 1549-56 by Celia Bygrave and Chris Cairns.

• Ranucci M, et al. Impact of oligon central venous catheters on catheter colonization and catheter-related bloodstream infection. Crit Care Med 2003; 31: 52-9 by David Swann.

• Solanki P. Chawla A. Garg R. Gupta R. Jain M. Sarin SK. Beneficial effects of terlipressin in hepatorenal syndrome: a prospective, randomized placebo-controlled clinical trial. Journal of Gastroenterology & Hepatology. 18(2):152-6, 2003 by Ewan Jack.

• Ronco C, et al. Effects of different doses in continuous veno-venous haemofiltration on outcomes of acute renal failure: a prospective randomised trial. Lancet 2000 Vol 356 (9223) 26-30 by Ewan Jack.

• Rhodes A, et al. A Randomised controlled trial of the pulmonary artery catheter in critically ill patients. Intensive Care Med. 2002;28:256-264 by Nityanand Lanka.

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Regards,

Chris Cairns

Chair, SICS EBMG

sicsebm@btinternet.com

Chris.Cairns@fvah.scot.nhs.uk