Web site designed and maintained by Chris Cairns  © SICS EBM Group 2004                                  

SICS EBMG Update No.5 July 2006

Welcome to the Scottish Intensive Care Societies Evidence-Based Medicine Groups fifth Update. As you will see we are publishing all of the CATs recently published in JICS. This is following the recent agreement between the ICS and the SICS. For more information on this venture please read the news section. Also, please remember that by popular demand we have created a yahoo discussion group. The aim of this is to facilitate discussion of issues raised on the site, or to enable feedback on any publications. To subscribe to the group please email to: icu_ebm-subscribe@yahoogroups.co.uk or visit http://uk.groups.yahoo.com/group/icu_ebm/

New Review

• Early tracheostomy: A review of the available evidence from a meta-analysis and its composite controlled studies. (6 CATS) By Richard Price, David Swann & Martin Hughes

 Updated Review

• EBM Reviews. Scottish Intensive Care Society EBM Group. Swann D. Using heat and moisture exchange filters reduces the incidence of ventilator-associated pneumonia. 2004. (Updated 2005, 2006).

New Critically Appraised Papers (Joint publications with JICS):

• Van den Berghe G, et al. Intensive Insulin Therapy in The Medical ICU. N Engl J Med 2006;354:449-61. by Chris Cairns

• Pearse et al. Early goal-directed therapy after major surgery reduces complications and duration of hospital stay. A randomised, controlled trial. Critical Care 2005, 9:R687-R693. by David Elliot

• Verheij J, et al. Effect of fluid loading with saline or colloids on pulmonary permeability, oedema and lung injury score after cardiac and major vascular surgery. Br J Anaesth 2006; 96 (1):21-30. by Rebecca Appelboam.

• Kruger P et al. Statin therapy is associated with fewer deaths in patients with bacteraemia. Intensive Care Med 2006; 32:75-79 by Niraj Niranjan

• Gershlick AH, Stephens-Lloyd A, Hughes S et al for the REACT Trial Investigators. Rescue angioplasty after failed thrombolytic therapy for acute myocardial infarction. N Engl J Med 2005; 353: 2758-68 by Stephen Harris

• The National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Efficacy and Safety of Corticosteroids for Persistent Acute Respiratory Distress Syndrome. NEJM 2006; 354: 1671-1684 by Brian Cuthbertson.

• Martin GS, Moss M, Wheeler A, Mealer M, Morris J, Bernard G: A randomised, controlled trial of furosemide with or without albumin in hypoproteinaemic patients with acute lung injury. Crit Care Med. 2005; 33:1681-7 by David MacNair & Brian Cuthbertson

• John V. Peter, et al. Effect of non-invasive positive pressure ventilation ( NIPPV) on mortality in patients with acute cardiogenic pulmonary oedema: a meta-analysis. Lancet 2006; 367: 1155-63 by Brian Digby.

Updated Stats Page

Regards,

Chris Cairns

Chair, SICS EBMG

sicsebm@btinternet.com

Chris.Cairns@fvah.scot.nhs.uk