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SICS EBM Update No.3 July 2005

 

Welcome to the Scottish Intensive Care Societies Evidence-Based Medicine Groups Third Update. The last 6 months have been a productive one. One revised review and 10 new CATs. Also news of website updates:

 

·         Updated Review:

 

·         Tidal volume limitation and PEEP in Acute Lung Injury and Acute Respiratory Distress Syndrome. By Dr Brian Cuthbertson

 

 

·         New Critically Appraised Papers:

 

·         Kress JP, et al. Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. NEJM 2000; 342: 1471-1477. By Tim Geary

 

·         Kress JP, et al. The long term psychological effects of daily sedative interruptions on critically ill patients. AJRCCM 2003; 168: 1457- 1461. By Tim Geary.

 

·         Effect of Glucose-Insulin-Potassium Infusion on Mortality in Patients With Acute ST-Segment Elevation Myocardial Infarction The CREATE-ECLA Randomized Controlled Trial. JAMA. 2005;293:437-446. By Paul McConnell.

 

·         Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic control. Crit Care Med 2003; Vol 31(2): 359-366. By Ryan Moffat.

 

·         M Holzer et al.: Hypothermia for neuroprotection after cardiac arrest: Systematic review and individual patient data meta-analysis, Critical Care Medicine 2005, Vol.33: 414-418. By Anja Beilharz.

 

·         Phua J, et al. Noninvasive ventilation in hypercapnic acute respiratory failure due to chronic abstructive pulmonary disease vs. other conditions: effectiveness and predictors of failure. Int Care Med 2005; 31:533-539. By Alice Murray.

 

·         Derek C Angus, et al. The effect of drotrecogin alfa (activated) on long-term survival after severe sepsis. Crit Care Med 2004;Vol 32; No 11: 2199-2206. By Caroline Hawe.

 

·         Plant PK. Owen JL. Elliott MW. Early use of non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease on general respiratory wards: a multicentre randomised controlled trial. Lancet. 2000 355(9219):1931-5. By Ewan Jack.

 

·         Mayer SA, et al. Recombinant Activated Factor VII for Acute Intracerebral Hemorrhage. NEJM 2005: 352(8); 777 – 785. By Ewan Jack.

 

·         Spragg RG, et al, Effect of Recombinant Surfactant Protein C- based Surfactant on the Acute Respiratory Distress Syndrome Engl J Med 2004; 351:884-92. By Basu Bhadrajkumar.

 

 

 

 

 

 

 

Next Update:

 

  • CVCrBSI Review (with 30 CATs!)

  • 10 more CATs (Including The MERIT study)

 

 

Regards,

 

 

Chris Cairns

Chair, SICS EBMG

sicsebm@btinternet.com